Just Bought!

[ATOEtalGeek]

Here's a few I can think of off the top of my head:
A main difference I can think of is that while there is a carry limit of one Item or Ally card per location plus three Town Items or Allies, there is not a limit to the number of items you can use in your turn or during a Fight. It's as though everything you have with you is equipped. And there is no concept of double-handed vs one-handed.

Another that comes to mind is the Villains have their own (sometimes) detailed abilities. To get the full thematic flavor and for best game play make sure you pay attention to those details so they are not missed. Early on we would finish a game and then go "Oh man, the Villain has an ability that is supposed to trigger every time X happened and we completely missed it. Crap!"

Keep an eye on and pay attention to Remains-in-Play Mystery cards and when they trigger. In pimping my game I actually made Shadow Track marker tokens that lay on the Shadow Track Stage delineations to help us remember stuff like that.

Unlike LNOE there is no "mission" from the get go (with the exception of a couple Villains I think in the Coast expansion). When you start any particular game you won't have a sense of "We have to get to building X to collect Y" or anything like that. You're goal is to develop your Hero's attributes but it's going to be fairly random for you especially until you learn where the good stuff is in the particular location decks. You will also need to go to spaces that grant Event cards as their powers will be essential.

The Town Elders is another element that will take some getting used to. These act a little differently whether you're playing competitively or in co-op. They can become essential against certain Villains though, especially ones like Sophie and her ability to cancel Mystery cards.